Horrifying moment plane nosedives and crashes into a motorway with cars driving through fireball aftermath in Italy

This is the horrifying moment a small plane nosedived and crashed into a busy motorway in Italy leaving at least two people dead.

Footage captured the moment the plane smashed into the road in Italy's Brescia province and exploded into a fireball, with vehicles forced to drive through the flames.

The aircraft was completely destroyed, with no one on board surviving the accident.

Meanwhile, the public prosecutor's office of Brescia has opened a case for manslaughter following, local newspaper Giornale di Brescia reported.

The horrific accident comes just days after an air force fighter jet crashed into a school in Bangladesh and killed 31 people, at least 25 of them children.

The children, many aged under 12, were about to return home from class on Monday when the Chinese-manufactured F-7 BGI Bangladesh Air Force jet ploughed into their school in Dhaka and burst into flames, trapping pupils in the fire and debris.

The military said it had suffered mechanical failure.

Television footage showed fire and smoke billowing from the site of the crash as bystander are seeing trying put out the flames.

Other clips circulating on social media show crowds of students fleeing from the scene in a panic.

It also comes a little over a month after an Air India plane crashed on top of a medical college hostel in neighbouring India's Ahmedabad city, killing 241 of the 242 people on board and 19 on the ground, marking the world's worst aviation disaster in a decade.